BPS Pharmacotherapy (Part1 and Part2) - BPS-Pharmacotherapy Exam Practice Test
Question 1
A patient presents at a physician's office with gait unsteadiness and clumsiness. The patient has a history of type 2 diabetes mellitus, hypertension, and chronic numbness and tingling of the feet and fingertips.
Examination reveals mild distal wasting, glove-and-stocking sensory impairment, absent ankle jerks, brisk knee jerks, and bilateral Babinski reflexes. Gait is slightly ataxic.
CBC reveals a hemoglobin of 10.1 g/dL, WBC of 4,500 cells/mL, MCV 120 fL, and platelets
163,000 cells/ul.
Which of the following is the most important laboratory test for assisting in diagnosis?
Examination reveals mild distal wasting, glove-and-stocking sensory impairment, absent ankle jerks, brisk knee jerks, and bilateral Babinski reflexes. Gait is slightly ataxic.
CBC reveals a hemoglobin of 10.1 g/dL, WBC of 4,500 cells/mL, MCV 120 fL, and platelets
163,000 cells/ul.
Which of the following is the most important laboratory test for assisting in diagnosis?
Correct Answer: B
Question 2
A 13-year-old boy who has asthma, weight 32kg, height 150cm, takes inhaled salmeterol one puff twice daily and inhaled fluticasone 2 puffs twice daily. The patient must stop participation in physical education classes after a few minutes due to shortness of breath. To allow the patient to participate longer, the most effective measure would be to add which of the following?
Correct Answer: C
Question 3
A pharmacotherapy specialist is evaluating a study that compared the effects of iron sucrose versus sodium ferric gluconate on ferritin levels in patients receiving hemodialysis. A significant difference was found between the groups. This study was conducted in a large academic center in Denmark; the specialist practices at a small rural hospital in Minnesota. Which of the following information in the paper will be most important in determining whether the study's results can be applied to the specialist's practice?
Correct Answer: C
Question 4
In a clinical trial, when would "intention to treat" analysis be most appropriate?
Correct Answer: B
Question 5
A 72-year-old man has chronic insomnia that has not responded to measures to improve sleep hygiene. The patient is not depressed and has no other chronic health problems. It is determined that medication use will probably be necessary to manage the insomnia. What is the best initial recommendation for this patient?
Correct Answer: A
Question 6
A 49-year-old man presents to his physician with a 3-day acute attack of gout in four joints of the right foot. The patient has a history of at least three previous gout attacks; in one, a joint aspirate was positive for urate crystals. His history also includes type 2 diabetes mellitus and two calcium oxalate kidney stones.
Laboratory values include creatinine 3.1 mg/dL, uric acid 11.7 mg/dL, and A1C 6.8%. The patient is allergic to aspirin. Vital signs are BP135/82mm Hg and HR 90 bpm and regular.
Current medications are glipizide 10 mg daily and enalapril 20 mg daily.
Which short-term regimen is most appropriate for treating this patient's gout?
Laboratory values include creatinine 3.1 mg/dL, uric acid 11.7 mg/dL, and A1C 6.8%. The patient is allergic to aspirin. Vital signs are BP135/82mm Hg and HR 90 bpm and regular.
Current medications are glipizide 10 mg daily and enalapril 20 mg daily.
Which short-term regimen is most appropriate for treating this patient's gout?
Correct Answer: D
Question 7
A 60-year-old man with heart failure states that he becomes "a bit short of breath" after climbing a flight of stairs. His ejection fraction is 40%. Current medications include lisinopril 5 mg daily, metoprolol XL 100 mg daily, aspirin 81 mg daily, furosemide 40 mg daily, and digoxin
250 mcg daily. All vital signs and laboratory values are stable and within normal limits. Which of the following recommendations would be most appropriate at this time?
250 mcg daily. All vital signs and laboratory values are stable and within normal limits. Which of the following recommendations would be most appropriate at this time?
Correct Answer: C
Question 8
The results of a drug-use evaluation study by the P & T Committee reveal that 15 prescribers are using an antibiotic inappropriately. Which of the following is the most effective strategy for improving the drug therapy?
Correct Answer: B
Question 9
Prednisone 10 mg orally daily is prescribed for a 68-year-old 60-kg patient with acute temporal arteritis. The pharmacotherapy specialist would recommend which of the following?
Correct Answer: B
Question 10
A 42-year-old woman is diagnosed with deep vein thrombosis. Heparin therapy is initiated with
5,000 units as a single bolus injection, followed by an initial infusion rate of 1,000 units/h. The aPTT measured 6 hours later is >150 sec. Which of the following would be the most appropriate action at this time?
5,000 units as a single bolus injection, followed by an initial infusion rate of 1,000 units/h. The aPTT measured 6 hours later is >150 sec. Which of the following would be the most appropriate action at this time?
Correct Answer: C
Question 11
Which of the following pharmacoeconomic analyses incorporates patient preferences regarding health?
Correct Answer: B
Question 12
An 18-year-old patient presents with abrasions on the hands, knees, and shoulder from a recent bicycle accident. Gram-staining of surgical incision and drainage specimens reveals Gram positive cocci in chains. The patient has necrotizing fasciitis and develops bronchospasms after being given penicillin. Which intravenous antibiotic would be best to use in place of penicillin?
Correct Answer: A
Question 13
The pharmacotherapy specialist-directed research team in a large healthcare system plans to submit a comparative effectiveness study proposal in response to the request for proposals released under the Patient Protection and Affordable Care Act. In designing this study, which category of outcomes should be used for the primary endpoint?
Correct Answer: B
