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American Society of Microbiology ABMM Exam Syllabus Topics:

American Society of Microbiology ABMM Sample Questions:

1. During a primary infection with Epstein-Barr virus (EBV), the virus establishes latency in B lymphocytes.
The transition from lytic to latent infection is tightly regulated by viral gene expression. Which of the following viral proteins is crucial for the establishment and maintenance of EBV latency and is a key target in EBV-associated lymphomas?

A) Early antigen (EA)
B) Epstein-Barr nuclear antigen 1 (EBNA1)
C) Glycoprotein gp350
D) Viral capsid antigen (VCA)

2. A patient with a history of travel to an area endemic for schistosomiasis presents with hematuria. Microscopic examination of a urine sediment reveals a large oval egg with a prominent terminal spine. The MOST likely causative agent is:

A) Schistosoma mansoni
B) Schistosoma haematobium
C) Schistosoma mekongi
D) Schistosoma japonicum

3. A microbiology laboratory is performing Gram staining on a bacterial smear. If the safranin counterstain is omitted, Gram-negative bacteria will appear:

A) Purple
B) Brown
C) Colorless
D) Blue

4. A microbiology laboratory is investigating a possible outbreak of Salmonella infection. Serological testing of patient isolates reveals they all possess the same O antigen but different H antigens. This suggests:

A) Contamination in the laboratory affecting multiple samples.
B) A single point source of infection with a genetically stable strain.
C) A common ancestral strain that has undergone flagellar antigen variation.
D) Multiple sources of infection with unrelated Salmonella strains.

5. A patient with a history of valvular heart disease undergoes a dental procedure and subsequently develops a bloodstream infection with Streptococcus mutans. This organism gains access to the bloodstream primarily due to:

A) Transient bacteremia resulting from the procedure.
B) Production of potent extracellular enzymes.
C) Formation of a protective biofilm on the teeth.
D) Active invasion of the oral mucosa.

Solutions: