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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A patient is started on ledipasvir-sofosbuvir. What would be the best indicator of treatment response?

A) HCV RNA below the lower limit of quantification
B) ALT less than three times the upper limit of normal
C) Absence of cryoglobulinemia
D) Absence of alpha-fetoprotein

2. A 46-year-old patient begins treatment with allopurinol 300 mg daily following the onset of an acute gout attack due to elevated uric acid.
The patient's other medications are:
* Cyclosporine 800 mg daily
* Prednisone 20 mg daily
* Azathioprine 100 mg daily
* Nifedipine extended release 90 mg daily
Several days later there was an observed decrease in the patient's WBC count. Which drug interaction with allopurinol is most likely to account for this change?

A) Azathioprine
B) Cyclosporine
C) Nifedipine
D) Prednisone

3. A 24-year-old Woman complains of dysuria, hesitancy in urination, and frequent urination for the past 2 days. She has no costovertebral tenderness, fever, or history of UTls. Urinalysis data are:
* pH: 5.5
* WBCS: 15 cells/ul
* RBCS:5 Cells/uL
* Bacteria: Numerous Gram-negative rods
* Negative for protein, glucose, and WBC casts
For this patient, assuming that local resistance rates are low, which of the following would be an empiric cost-effective regimen?

A) Sulfamethoxazole/trimethoprim one double-strength tablet twice daily for 3 days
B) Azithromycin 1 g single dose
C) Ciprofloxacin 500mg twice daily for 7 days
D) Amoxicillin 500 mg three times daily for 7 days

4. Which of the following is the best initial strategy in addition to docusate sodium to prevent constipation in a 45-year-old patient initiating around-the-clock morphine therapy for chronic pain associated with malignancy?

A) Glycerin suppository
B) Senna
C) Magnesium citrate
D) Psyllium

5. A patient presents to the emergency department with an acute Ischemic stroke. The symptoms have been present for just over an hour.
Which test would be most appropriate to help determine the patient's eligibility to receive t-PA?

A) Cerebral angiogram
B) CT scan
C) Neurologic exam
D) MRI

Solutions: